DON’T LET COSMETIC COMPANIES CON YOU

Do you believe cosmetics can reverse the signs of aging? It would be wonderful, if true.

The US Food and Drug Administration (FDA) just again issued warnings to cosmetic companies, including Avon; Lancôme (a subsidiary of L’Oreal); Andes Natural Skin Care based in Nevada and Jason Beckett, located in New Jersey. All of the FDA letters alleged the firms marketed their products using improper claims. Simply, if a cosmetic could really cure wrinkles, they would be a drug and not cosmetic, which is not to change your body’s structures or functioning. The testing of drug costs millions while, in fact, anyone can mix things in his or her kitchen and put it on the market as a cosmetic.

Will the FDA’s latest efforts bring about any changes? Maybe in the names of the anti-aging products but the FDA is poor and the big cosmetic manufactures have millions to fight any court case against them

I believed I was early in the fight against false claims by cosmetic companies with my book: A Consumer’s Dictionary of Cosmetic Ingredients first published by Crown in 1972 and today in its Seventh Edition. I received information about forthcoming legislations regarding cosmetics and other consumer products from senators such as the late Ted Kennedy. Nothing came of their efforts in Congress.

I have to admit that I and all the other consumer groups were late in game. In researching this subject. I found journal papers from as far back as 1960 citing the problem about false advertising by cosmetic firms. One I liked most was from: 16 Business Law.81 (1960-1961) Federal Trade Commission Regulation of Food, Drug And Cosmetic Advertising by Earl W. Kintner, Chairman of the Federal Trade Commission. He wrote” The most cursory backward glance instantly reveal that the false and misleading description of foods, drugs and cosmetics has plagued mankind since the days of the first witch doctor.”

In 1960, when Kintner was Chairman of the FTC, 560 complaints were filed 410 orders involving monopolies and 359 complaints against deceptive practices. His prior job as a member of the UN’s War Crimes Commission in London was apparently a lot easier. The Commission just had to prove guilt and rule on  punishment for felons. The Commission would have the very difficult  job  of convincing  today’s age-panicked consumers of  cosmetic fraud.  People are willing to pay sometimes very big money for  products promoted to hold back the wrinkles of time.

The only way to combat false advertising of cosmetics is by you and other consumers knowing the facts. Cosmetic companies are very sensitive to bad publicity. It can waste almost all the money spent on promotion. And sometimes, cosmetics can contain potentially harmful ingredients.

Johnson and Johnson, for example, makers of Aveno, Neutrogena and Johnson Baby Shampoo recently announced it would be removing carcinogens and other toxic chemicals from baby and adult products.

I believe that being able to look up ingredients in my Consumer’s Dictionary of 
Cosmetic Ingredients 
helped but the major credit which made J&J take action is very much due to The Campaign for Safe Cosmetics, a national coalition of more than 175 nonprofit organizations working to eliminate dangerous chemicals from cosmetics and led by The Breast Cancer Fund; Clean Water Action; Commonweal; Environmental Working Group (EWG) ;Friends of the Earth, and Women’s Voices for the Earth. The research they accumulated and the pressure they put on politicians and companies has been very powerful. The coalition did emphasize harmful ingredients but I believe that when they made their findings public it was a major factor in bringing about the beginning of change in the freewheeling cosmetic industry.

As far as false advertising, I like the observation one of my friends sent me via e-mail: “Relax: At least wrinkles don’t hurt!”

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THE NEW CAR SMELL MAY BE STINKY

The Internet and TV media are having fun about the “dangers” of the “New Car Smell” which subliminally lures the buyer even of a used car to be more prone to opt for the vehicle. The new car smell, which becomes especially pungent after the car has been sitting in the sun for a few hours, is partly the pungent odor of phthalates along with many other chemicals volatilizing in the closed environment of the vehicle.

It is not so humorous when you consider the chemicals are inhaled and added to the many toxic volatile chemicals in your environment including your home, your office and your yard. In fact, I wrote a book about it, A Consumer’s Dictionary of Household, Yard and Office Chemicals first published by Crown in 1992 and now available as an updated E-book.

Phthalates, derived from the organic chemical phthalic acid, include a large group of chemicals. World production of phthalates is estimated to be several million tons a year. . Phthalate compounds are used in just about every major product category including cosmetics, construction, automotive, household, apparel, toys packaging and medicinal material. You undoubtedly have phthalates in your body. The US Centers for Disease Control and Prevention has detected phthalates in the urine of every Americans tested. Minute levels of phthalates used in toys, building materials, drug capsules, cosmetics and perfumes, have been statistically linked to sperm damage in men and genital changes, asthma and allergies in children. .Recent observations indicate some phthalates may be mutagenic, and cancer-causing

In 2004, the European Union banned phthalates in nailpolish. The FDA said in 2004 that phthalates are safe for humans in the amounts to which we are exposed. In 2008, The National Research Council (NRC) launched a project funded by the Environmental Protection Agency (EPA) to investigate the potential health effects of phthlates including accumulative risks

Cynics say there are so many reports of minute amount of toxins and there is really nothing to worry about. It’s the dose that counts. But I always say tell me how much of a carcinogen causes cancer and what is the effect of the chemicals around us, in us and on us?, Here’s a pertinent quote, I believe, from my A Consumer’s Dictionary of Household, Yard and Office Chemicals by Devra Davis, PhD, MPH, Director, Center for Environmental Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA, At the Annual Conference of the American Medical Writers Association in 2005. She said among the reasons scientists believe in environmental causes of cancer:

  • Fewer than 1 in 10 cases of breast cancer occur in women born with genetic defects. The others are believed to be environmental.
  • The cancer risk for adopted children reflects their adoptive parents, not their biologic parents.
  • Fewer than half of identical twins get the same cancer.
  • Rates of cancer are higher for people employed outside the home.
  • The cancer risk for immigrants changes to that of their new country.
  • The majority of cancer cases have no known risk factors.
  • Disease is more aggressive in women with higher residues of toxins in their blood.

Manufacturers say there is no reliable evidence that phthalates cause any health problems. Newly identified markers are providing a better indication of our exposure to phthalates. So next time you sniff at the potential of adverse effects of the “New Car Scent” don’t laugh. That new car smell, which becomes especially noticeable after the car has been sitting in the sun for a few hours, is partly the pungent odor of phthalates volatilizing and many other chemicals floating around the enclosed environment of your car, especially if the temperature is high.

New Kind of Alzheimer’s Drug May Prevent or Treat The Disease

Daniel Chain,Ph.D, the son of a Nobel Prize Winner and a distinguished neurobiologist  himself, woke up one Sunday night 1996 and had a sudden inspiration– “Why not monocolonal antibodies?”

Chairman and chief executive officer of Manhattan-based Intellect Neurosciences, Dr. Chainwas interested in finding an innovative medication that can slow down, arrest and ultimately prevent Alzheimer’s disease – a devastating condition afflicting 30 million people worldwide. Contrary to current drugs on the market, which only treat symptoms, Dr. Chain’s aim was to create a new class of disease-modifying Alzheimer’s drugs that attack the underlying pathologies.

 Monclonal Antibodies

 Moncolonal antibodies are a type of protein made in the laboratory designed  to find and bind to a specific substance. Could a monoclonal antibody be developed that would latch on to amyloid, a dense deposit of protein found as plaques on the cells and nerves of Alzheimer’s patients at autopsy? There is no unanimous agreement that amyloid plaques are the cause of the condition but may be just a symptom or an extraneous factor.

Amyloid plaques were first noted by Dr. Louis Alzheimer’s in 1906 . The main constituent of the plaques is the Beta Amyloid protein which is comprised of fragments of a much larger protein called the Amyloid Precursor Protein (APP) implicated in regulating numerous physiological functions in the body.  Beta Amyloid can accumulate for different reasons in the brain.  The naturally sticky fragments form clumps that increase in number and density until eventually, the clumps deposit as insoluble plaques onto the surface of nerve cells. Are these plaques toxic? Are they beneficial?  Do their roles change at different stages of the disease? As the plaques mature in the brain do they trigger inflammation which damages the cells causing them to die?

Toxic Substance Floating In Brain Fluid

 Dr. Chain now believes that there is a toxic substance floating around in brain fluid that is a precursor to amyloid clumps and plaques.

 “Perhaps,” he reasons, “the plaques of hardened amyloid found on the brain cells of Alzheimer’s patients may be the way the brain actually protects itself from the toxic amyloid precursor.”

Drug Companies At Work On The New Type of Drug

He says  he decided to develop a method of harnessing certain monoclonal antibodies that he believes can be used to render the precursor harmless and thus prevent or improve Alzheimer’s destruction of the brain cells.

Dr. Chain was successful and he patented the technique he developed for amyloid precursor seeking monoclonal antibodies. He calls it Antisenilin for anti-senility. His invention is currently being used by several of the world’s largest pharmaceutical companies which have taken licenses to Dr. Chain’s patents from which Intellect Neurosciences stands to obtain royalties from sales if and when the drugs are approved by the FDA . The most advanced product, Bapineuzumab, is in Phase 3 clincal trials involving several thousand Alzheimer’s patients world-wide. Bapineuzumab is being co-developed by Wyeth/Pfizer and Johnson & Johnson.  Dr. Chain’s patents have already been granted in Europe, Japan, China and elsewhere

Dr. Chain points out there are two basic types of Alzheimer’s. One that occurs in 5 to 10 percent relatively early at 40-50 years and invariably has a genetic pre-disposition carried in families. The other starts later– about 65 years and up –and has known and unknown causes.

He said the tests first conducted with bapineuzumab, involved a small group about 250 patients: “The researchers did not separate out those with the gene for the disease and those who developed Alzheimer’s later in life. Results did seem to indicate that those who developed it later in life were benefited by the drug but not those who carried the gene.”

Studies involving several thousand people –separating the two types of Alzheimer’s—are now underway.

Bapineuzumab May Be On The Market Within Three Years

Dr. Chain said he hopes that within three years, bapineuzumab will be on the market.

What about side-effects?

So far, he said, he, there is some edema—(swelling) –but it goes away and in lower doses it does not occur at all.